SPY vs ZTS: SPDR S&P 500 ETF Trust vs Zoetis Inc. Historical Returns & Investment Comparison

This SPY vs ZTS comparison analyzes the historical stock performance of SPDR S&P 500 ETF Trust and Zoetis Inc. side-by-side. Using real, adjusted market data, this tool shows how identical investments in both stocks would have performed over time—highlighting differences in returns, volatility, and consistency across market cycles.

Use the interactive calculator below to adjust the investment amount and time period, visualizing how SPDR S&P 500 ETF Trust and Zoetis Inc. have historically performed against each other.

Company Profiles

1

SPDR S&P 500 ETF Trust

SPY

SPY is the first exchange-traded fund (ETF) listed in the US. It is designed to track the S&P 500 Index, which measures the performance of the large-cap segment of the US equity market.

Key Innovations

  • First US-listed ETF

Business Segments

  • ETF
    Passive investment vehicle tracking the S&P 500.
2

Zoetis Inc.

ZTS

Zoetis is the world's leading animal health company. It discovers, develops, manufactures and commercializes medicines, vaccines, diagnostics and other technologies for companion animals and livestock.

Key Innovations

  • Apoquel and Cytopoint (dermatology)
  • Librela and Solensia (monoclonal antibodies for pain)

Business Segments

  • United States
    Operations in the US.
  • International
    Operations outside the US.

How This Comparison Works

Our stock comparison tool uses adjusted closing prices to calculate year-by-year returns for both stocks. This ensures an apples-to-apples comparison that accounts for:

  • Dividends: All dividend payments are reinvested
  • Stock splits: Historical prices are adjusted for all splits
  • Head-to-head record: Shows which stock outperformed each year
  • Statistical analysis: Average returns, best/worst years, and win rates

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Important Disclaimer

This comparison tool is for educational and informational purposes only and does not constitute financial, investment, or trading advice. Past performance is not indicative of future results. Historical returns include dividends and stock splits but do not account for taxes, fees, inflation, or individual circumstances. Stock market investments carry risk, including the potential loss of principal. Always consult with a qualified financial advisor before making investment decisions. The data presented is based on historical market data and may contain inaccuracies or delays.