SPY vs TECH: SPDR S&P 500 ETF Trust vs Bio-Techne Corporation Historical Returns & Investment Comparison

This SPY vs TECH comparison analyzes the historical stock performance of SPDR S&P 500 ETF Trust and Bio-Techne Corporation side-by-side. Using real, adjusted market data, this tool shows how identical investments in both stocks would have performed over time—highlighting differences in returns, volatility, and consistency across market cycles.

Use the interactive calculator below to adjust the investment amount and time period, visualizing how SPDR S&P 500 ETF Trust and Bio-Techne Corporation have historically performed against each other.

Compare Stock Performance

Select two stocks and an investment amount to see how they compare over time.

Compare any two stocks to see which performed better historically

Performance Summary

$10,000 invested from 1993 to 2025 (33 years)

Head-to-Head Record

14
SPY Wins
0
Ties
19
TECH Wins

Over the 33-year comparison period, SPDR S&P 500 ETF Trust outperformed Bio-Techne Corporation in 14 years, while Bio-Techne Corporation outperformed SPDR S&P 500 ETF Trust in 19 years.

SPY - SPDR S&P 500 ETF Trust

Average Annual Return:+11.71%
Best Year:+37.39% (1995)
Worst Year:-36.24% (2008)
Win Rate:81.8% (27/33 years)
Total Value:$250,597.02
Total Gain:+$240,597.02 (+2405.97%)

TECH - Bio-Techne Corporation

Average Annual Return:+29.05%
Best Year:+308.00% (1991)
Worst Year:-36.23% (1993)
Win Rate:64.9% (24/37 years)
Total Value:$7,701,763.22
Total Gain:+$7,691,763.22 (+76917.63%)

Overall Winner: TECH with an average annual return of 29.05% (vs 11.71% for SPY)

Understanding SPY vs TECH Performance

When comparing SPDR S&P 500 ETF Trust and Bio-Techne Corporation, investors should consider multiple factors beyond just total returns. Volatility, consistency of growth, dividend payments, and sector-specific risks all play crucial roles in determining which stock might be better suited for your investment strategy and risk tolerance.

Historical performance data shows how each stock responded to market downturns, economic expansions, and company-specific events. While past performance doesn't guarantee future results, understanding these patterns can help inform investment decisions and portfolio allocation strategies.

Cumulative Growth Comparison

A $10,000 investment in SPDR S&P 500 ETF Trust grew to $250,597, compared to $7,701,763 for Bio-Techne Corporation over the same period.

Year-by-Year Comparison

YearSPY ReturnSPY CumulativeTECH ReturnTECH CumulativeDifferenceWinner
1993 (Start)-$10,000.00-$10,000.00-Initial Investment
1994+8.71%$10,870.91-36.23%$63,185.20+44.94% (SPY)SPY
1995+0.67%$10,943.47-$63,185.20+0.67% (SPY)SPY
1996+37.39%$15,035.16+101.25%$127,160.31-63.86% (TECH)TECH
1997+21.20%$18,223.19+30.82%$166,348.01-9.61% (TECH)TECH
1998+33.14%$24,261.81+40.00%$232,887.26-6.86% (TECH)TECH
1999+28.03%$31,063.11+14.19%$265,932.12+13.84% (SPY)SPY
2000+20.66%$37,482.18+160.65%$693,154.07-139.99% (TECH)TECH
2001-8.85%$34,165.23+24.09%$860,107.30-32.94% (TECH)TECH
2002-10.13%$30,703.75+9.39%$940,851.72-19.52% (TECH)TECH
2003-22.42%$23,820.14-20.64%$746,616.39-1.77% (TECH)TECH
2004+24.18%$29,580.86+30.53%$974,541.33-6.34% (TECH)TECH
2005+10.75%$32,760.13+2.37%$997,622.88+8.38% (SPY)SPY
2006+5.32%$34,504.59+46.46%$1,461,130.51-41.14% (TECH)TECH
2007+13.84%$39,281.03-2.65%$1,422,396.45+16.49% (SPY)SPY
2008+5.33%$41,375.53+17.59%$1,672,588.66-12.26% (TECH)TECH
2009-36.24%$26,382.38-3.50%$1,614,107.53-32.74% (TECH)TECH
2010+22.65%$32,359.23+8.18%$1,746,091.41+14.48% (SPY)SPY
2011+13.14%$36,610.39-2.73%$1,698,385.68+15.87% (SPY)SPY
2012+0.85%$36,922.44+4.23%$1,770,300.70-3.38% (TECH)TECH
2013+14.17%$42,154.69+1.33%$1,793,910.94+12.84% (SPY)SPY
2014+29.00%$54,380.19+38.79%$2,489,789.10-9.79% (TECH)TECH
2015+14.56%$62,298.86-0.55%$2,476,117.60+15.11% (SPY)SPY
2016+1.29%$63,101.60-0.25%$2,469,936.91+1.54% (SPY)SPY
2017+13.59%$71,674.43+18.09%$2,916,800.62-4.51% (TECH)TECH
2018+20.78%$86,569.38+27.68%$3,724,108.16-6.90% (TECH)TECH
2019-5.25%$82,026.91+10.97%$4,132,597.11-16.22% (TECH)TECH
2020+31.09%$107,527.02+55.69%$6,434,185.04-24.61% (TECH)TECH
2021+17.24%$126,059.55+45.43%$9,357,195.40-28.19% (TECH)TECH
2022+30.51%$164,514.60+64.92%$15,431,874.07-34.41% (TECH)TECH
2023-18.65%$133,838.54-31.79%$10,525,368.73+13.15% (SPY)SPY
2024+26.71%$169,585.78-6.10%$9,883,619.14+32.81% (SPY)SPY
2025+25.59%$212,981.61-5.70%$9,320,660.56+31.29% (SPY)SPY
2026+17.66%$250,597.02-17.37%$7,701,763.22+35.03% (SPY)SPY

Annual returns include dividends and stock splits. Cumulative values show growth of $10,000 invested from the first year. Positive difference means SPY outperformed TECH that year.

Company Profiles

1

SPDR S&P 500 ETF Trust

SPY

SPY is the first exchange-traded fund (ETF) listed in the US. It is designed to track the S&P 500 Index, which measures the performance of the large-cap segment of the US equity market.

Key Innovations

  • First US-listed ETF

Business Segments

  • ETF
    Passive investment vehicle tracking the S&P 500.
2

Bio-Techne Corporation

TECH

Bio-Techne is a leading developer and manufacturer of high-quality purified proteins and reagent solutions, which are used by life science and clinical diagnostic industries.

Key Innovations

  • Purified cytokines and growth factors
  • Automated Western blot systems

Business Segments

  • Protein Sciences
    Reagents, instruments, and services for protein research.
  • Diagnostics and Genomics
    Clinical diagnostic reagents and genomic analysis.

How This Comparison Works

Our stock comparison tool uses adjusted closing prices to calculate year-by-year returns for both stocks. This ensures an apples-to-apples comparison that accounts for:

  • Dividends: All dividend payments are reinvested
  • Stock splits: Historical prices are adjusted for all splits
  • Head-to-head record: Shows which stock outperformed each year
  • Statistical analysis: Average returns, best/worst years, and win rates

Share This Comparison

Important Disclaimer

This comparison tool is for educational and informational purposes only and does not constitute financial, investment, or trading advice. Past performance is not indicative of future results. Historical returns include dividends and stock splits but do not account for taxes, fees, inflation, or individual circumstances. Stock market investments carry risk, including the potential loss of principal. Always consult with a qualified financial advisor before making investment decisions. The data presented is based on historical market data and may contain inaccuracies or delays.