MRNA vs PFE: Moderna, Inc. vs Pfizer Inc. Historical Returns & Investment Comparison
This MRNA vs PFE comparison analyzes the historical stock performance of Moderna, Inc. and Pfizer Inc. side-by-side. Using real, adjusted market data, this tool shows how identical investments in both stocks would have performed over time—highlighting differences in returns, volatility, and consistency across market cycles.
Use the interactive calculator below to adjust the investment amount and time period, visualizing how Moderna, Inc. and Pfizer Inc. have historically performed against each other.
Company Profiles
Moderna, Inc.
MRNA
Moderna is a biotechnology company pioneering a new class of medicines made of messenger RNA (mRNA). Its platform enables the development of vaccines and therapeutics for infectious diseases, immuno-oncology, and rare diseases.
Key Innovations
- ✓mRNA technology platform
- ✓Spikevax (COVID-19 vaccine)
Business Segments
- Infectious DiseasesCOVID-19 vaccines, flu vaccines, RSV vaccines.
- OncologyPersonalized cancer vaccines.
Pfizer Inc.
PFE
Pfizer is a world-leading biopharmaceutical company. It discovers, develops, manufactures, and markets healthcare products, including medicines and vaccines.
Key Innovations
- ✓Comirnaty (COVID-19 vaccine)
- ✓Paxlovid (COVID-19 antiviral)
- ✓Lipitor (historically highest selling drug)
Business Segments
- Primary CareInternal medicine, vaccines, and COVID-19 products.
- Specialty CareInflammation, immunology, rare diseases, and hospital products.
- OncologyCancer treatments (includes Seagen acquisition).
How This Comparison Works
Our stock comparison tool uses adjusted closing prices to calculate year-by-year returns for both stocks. This ensures an apples-to-apples comparison that accounts for:
- ✓Dividends: All dividend payments are reinvested
- ✓Stock splits: Historical prices are adjusted for all splits
- ✓Head-to-head record: Shows which stock outperformed each year
- ✓Statistical analysis: Average returns, best/worst years, and win rates
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Important Disclaimer
This comparison tool is for educational and informational purposes only and does not constitute financial, investment, or trading advice. Past performance is not indicative of future results. Historical returns include dividends and stock splits but do not account for taxes, fees, inflation, or individual circumstances. Stock market investments carry risk, including the potential loss of principal. Always consult with a qualified financial advisor before making investment decisions. The data presented is based on historical market data and may contain inaccuracies or delays.