MRK vs SPY: Merck & Co., Inc. vs SPDR S&P 500 ETF Trust Historical Returns & Investment Comparison
This MRK vs SPY comparison analyzes the historical stock performance of Merck & Co., Inc. and SPDR S&P 500 ETF Trust side-by-side. Using real, adjusted market data, this tool shows how identical investments in both stocks would have performed over time—highlighting differences in returns, volatility, and consistency across market cycles.
Use the interactive calculator below to adjust the investment amount and time period, visualizing how Merck & Co., Inc. and SPDR S&P 500 ETF Trust have historically performed against each other.
Company Profiles
Merck & Co., Inc.
MRK
Merck & Co., known as MSD outside the United States and Canada, is a global healthcare company that delivers innovative health solutions through its prescription medicines, vaccines, biologic therapies, and animal health products.
Key Innovations
- ✓Keytruda (cancer immunotherapy)
- ✓Gardasil (HPV vaccine)
- ✓Molnupiravir (COVID-19 antiviral)
Business Segments
- PharmaceuticalKeytruda, Gardasil, Januvia.
- Animal HealthVeterinary pharmaceuticals and vaccines.
SPDR S&P 500 ETF Trust
SPY
SPY is the first exchange-traded fund (ETF) listed in the US. It is designed to track the S&P 500 Index, which measures the performance of the large-cap segment of the US equity market.
Key Innovations
- ✓First US-listed ETF
Business Segments
- ETFPassive investment vehicle tracking the S&P 500.
How This Comparison Works
Our stock comparison tool uses adjusted closing prices to calculate year-by-year returns for both stocks. This ensures an apples-to-apples comparison that accounts for:
- ✓Dividends: All dividend payments are reinvested
- ✓Stock splits: Historical prices are adjusted for all splits
- ✓Head-to-head record: Shows which stock outperformed each year
- ✓Statistical analysis: Average returns, best/worst years, and win rates
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Important Disclaimer
This comparison tool is for educational and informational purposes only and does not constitute financial, investment, or trading advice. Past performance is not indicative of future results. Historical returns include dividends and stock splits but do not account for taxes, fees, inflation, or individual circumstances. Stock market investments carry risk, including the potential loss of principal. Always consult with a qualified financial advisor before making investment decisions. The data presented is based on historical market data and may contain inaccuracies or delays.